Helps you lose more weight than dieting alone. alli is the only FDA approved, over-the-counter weight loss aid. alli contains orlistat, which helps about 25% of the fat you eat from being absorbed. For every 2 pounds your lose through diet and exercise, alli can help you lose one more. alli (orlistat 60mg capsules) is a weight loss aid for overweight adults, 18 years and older, when used along with a reduced-calorie and low-fat diet. Follow label directions. alli Companion Guide Book offers tips, tools and help for setting weight loss goals.